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1.
Artigo em Inglês | MEDLINE | ID: mdl-38083739

RESUMO

A lab-on-a-chip multichannel sensing platform for biomedical analysis based on optical silicon nitride (SiNx) microring-resonators (MRR) was established. The resonators were surface functionalized and finally combined with a microfluidic chamber for validation using an avidin-biotin ligand-binding assay. The results with a limit of detection (LOD) of 2.3∙10-5 and a mean intra-assay coefficient of variation (CV) of ±10.0 %, also under consideration of FDA guidelines, show promising future applicability for a wide variety of targets in the field of outpatient medical diagnostics and life science.Clinical Relevance- Biomarkers play a crucial role in physiological processes of the human body. To enable instantaneous and decentralized analysis of these markers, systems are needed that can be used in a laboratory-independent environment with minimal amounts of biofluid. An example is the utilization of such systems for neonates or infants.


Assuntos
Técnicas Biossensoriais , Óptica e Fotônica , Recém-Nascido , Humanos , Técnicas Biossensoriais/métodos , Fótons , Compostos de Silício
2.
Opt Express ; 30(25): 44701-44716, 2022 Dec 05.
Artigo em Inglês | MEDLINE | ID: mdl-36522889

RESUMO

For wireless networks beyond 5G, directivity and reconfigurability of antennas are highly relevant. Therefore, we propose a linear antenna array based on photodiodes operating at 300 GHz, and an optical phased array based on polymer waveguides to orchestrate the antennas. Due to its low thermal conductivity and high thermo-optical coefficient, the polymer chip enables highly efficient and crosstalk-free phase shifting. With these, we demonstrate purely photonic-controlled beam steering across 20°. Compared to a single emitter, the 3-dB beam width is reduced by 8.5° to 22.5° and the output power is >10 dB higher. Employing Snell's law for coupling into air, we can precisely predict the radiation patterns.

3.
Sci Rep ; 8(1): 3018, 2018 02 14.
Artigo em Inglês | MEDLINE | ID: mdl-29445213

RESUMO

We report for the first time the successful wavelength stabilization of two hybrid integrated InP/Polymer DBR lasers through optical injection. The two InP/Polymer DBR lasers are integrated into a photonic integrated circuit, providing an ideal source for millimeter and Terahertz wave generation by optical heterodyne technique. These lasers offer the widest tuning range of the carrier wave demonstrated to date up into the Terahertz range, about 20 nm (2.5 THz) on a single photonic integrated circuit. We demonstrate the application of this source to generate a carrier wave at 330 GHz to establish a wireless data transmission link at a data rate up to 18 Gbit/s. Using a coherent detection scheme we increase the sensitivity by more than 10 dB over direct detection.

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